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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI4KB All Species: 34.85
Human Site: S445 Identified Species: 69.7
UniProt: Q9UBF8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UBF8 NP_002642.1 816 91379 S445 T H E Q R A G S F S T V P N Y
Chimpanzee Pan troglodytes XP_001171600 816 91257 S445 T H E Q R A G S F S T V P N Y
Rhesus Macaque Macaca mulatta XP_001106422 828 92728 S457 T H E Q R A G S F S T V P N Y
Dog Lupus familis XP_540314 945 105487 S574 T H E Q R A G S F S T V P N Y
Cat Felis silvestris
Mouse Mus musculus Q8BKC8 816 91497 S445 T H E Q R A G S F S T V P N Y
Rat Rattus norvegicus O08561 816 91637 S445 T H E Q R A G S F S T V P N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423394 743 82507 F418 E V L E C D N F D T A N V P A
Frog Xenopus laevis Q6GN16 804 90437 S433 T H E Q R A S S F T T V P N Y
Zebra Danio Brachydanio rerio Q49GP3 835 94040 S464 T P D Q R A S S F S T V P N Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524822 1674 181956 S1262 S H Q H L S C S R T S S C S S
Honey Bee Apis mellifera XP_391922 1078 119863 S678 Q S N V M G S S N I S A S E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39104 1066 119905 Y517 N S A E K V P Y L L L I E Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.1 84.2 N.A. 98.5 97.6 N.A. N.A. 78.6 85.2 74.9 N.A. 25.7 42.1 N.A. N.A.
Protein Similarity: 100 99.2 98.3 84.9 N.A. 99.1 98.6 N.A. N.A. 83.4 90 82.7 N.A. 36.2 55.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 86.6 80 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 93.3 86.6 N.A. 53.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 67 0 0 0 0 9 9 0 0 9 % A
% Cys: 0 0 0 0 9 0 9 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 9 0 0 0 0 0 0 % D
% Glu: 9 0 59 17 0 0 0 0 0 0 0 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 9 67 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 50 0 0 0 0 0 0 0 0 % G
% His: 0 67 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 9 0 0 0 9 9 9 0 0 0 9 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 9 0 9 0 0 9 0 67 0 % N
% Pro: 0 9 0 0 0 0 9 0 0 0 0 0 67 9 0 % P
% Gln: 9 0 9 67 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 67 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 9 17 0 0 0 9 25 84 0 59 17 9 9 9 9 % S
% Thr: 67 0 0 0 0 0 0 0 0 25 67 0 0 0 9 % T
% Val: 0 9 0 9 0 9 0 0 0 0 0 67 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 67 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _